SLOT THR777 - AN OVERVIEW

slot thr777 - An Overview

slot thr777 - An Overview

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There aren't any citations for germline classification of this variant in ClinVar. If you realize of citations for this variation, be sure to look at submitting that information to ClinVar.

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The distributing Business for this submitted (SCV) document. This column also consists of the SCV accession and Variation range, the date this SCV very first appeared in ClinVar, and also the day that this SCV was last current in ClinVar.

03%). This variant has not been claimed from the literature in persons impacted with GAA-associated conditions. ClinVar incorporates an entry for this variant (Variation ID: 574387). Variants that disrupt the consensus splice web-site are a relatively typical reason behind aberrant splicing (PMID: 17576681, 9536098). Algorithms developed to forecast the impact of sequence modifications on RNA splicing suggest this variant might build or improve a splice web site. In summary, the available proof is presently inadequate to determine the job of this variant in sickness. As a result, it's been categorized to be a Variant of Uncertain Significance. Okay

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Go through our procedures for calculating the overview position. This column also includes a url to the submitter’s assertion requirements if delivered, and the collection technique.

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The global slight allele frequency calculated because of the a thousand Genomes Challenge. The minor allele at this location is indicated in parentheses and may be various from your allele represented by this VCV file.

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